Back to search

Article

Evolution from adherent to suspension – systems biology of HEK293 cell line development

2020-01-30

Abstract excerpt

The need for new safe and efficacious therapies has led to an increased focus on biologics produced in mammalian cells. The human cell line HEK293 has bio-synthetic potential for human-like production and is today used for manufacturing of several therapeutic proteins and viral vectors. Despite this increasing popularity there is still limited knowledge of the detailed genetic and composition of derivatives of thi...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
ad5c38a6-714d-5b26-ba7b-622a8bb77d7e
DOI
10.1101/2020.01.29.924894
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Evolution from adherent to suspension – systems biology of HEK293 cell line developmentDOI 10.1101/2020.01.29.924894
Select a neighboring publication to make it the new centre.