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Comparative Transcriptomic Analyses of a Vero Cell Line in Suspension versus Adherent Culture Conditions

30 Aug 2023

Abstract excerpt

The Vero cell line is the most used continuous cell line for viral vaccine manufacturing. Its anchorage-dependent use renders scaling up challenging and operations very labor-intensive which affects cost effectiveness. Thus, efforts to adapt Vero cells to suspension cultures have been invested, but hurdles such as the long doubling time and low cell viability remain to be addressed. In this study, building on the...

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PMID: 37680537
DOI: 10.1155/2023/9364689

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