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Article

Multi-omics profiling of CHO parental hosts reveals cell line-specific variations in bioprocessing traits

2019-01-31

Abstract excerpt

Chinese hamster ovary (CHO) cells are the most prevalent mammalian cell factories for producing recombinant therapeutic proteins due to their ability to synthesize human-like post-translational modifications and ease of maintenance in suspension cultures. Currently, a wide variety of CHO host cell lines have been developed; substantial differences exist in their phenotypes even when transfected with the same targe...

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Identifiers and source

Literature Corpus work
982d22af-cc4f-544f-97a7-91ea233a7c98
DOI
10.1101/532150
Open publication

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Multi-omics profiling of CHO parental hosts reveals cell line-specific variations in bioprocessing traitsDOI 10.1101/532150
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