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Tumour evolution in ovarian cancer using high-throughput genomics technologies

2012-01-01

Abstract excerpt

High-grade serous ovarian carcinoma (HGSOC) is characterised by genomic instability, ubiquitous TP53 loss, widespread disease at diagnosis and the frequent emergence of platinum resistance. This thesis explores the use of high-throughput genomics technologies to understand if resistance could be explained by the model of tumour evolution. We performed SNP array analysis of a cell line model system of platinum resi...

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Literature Corpus work
ad52682b-2439-5fcd-ab73-33d298d5a330
DOI
10.17863/cam.11768
Open publication

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Tumour evolution in ovarian cancer using high-throughput genomics technologiesDOI 10.17863/cam.11768
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