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A Multivariate Genome-Wide Association Study Reveals Neural Correlates and Common Biological Mechanisms of Psychopathology Spectra

2024-04-08

Abstract excerpt

<title>Abstract</title> <p>There is considerable comorbidity across externalizing and internalizing behavior dimensions of psychopathology. We applied genomic structural equation modeling (gSEM) to genome-wide association study (GWAS) summary statistics to evaluate the factor structure of externalizing and internalizing psychopathology across 16 traits and disorders among European-ancestry individuals (n’s = 16,4...

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Literature Corpus work: ad1c124a-6bfe-507f-bad4-83ba553b9470
DOI: 10.21203/rs.3.rs-4228593/v1

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