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Disentangling differing relationships between internalizing disorders and alcohol use.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Jul 2024

Brasher Maizy S, Grotzinger Andrew D, Friedman Naomi P, Smolker Harry R, Evans Luke M

Abstract excerpt

Both internalizing disorders and alcohol use have dramatic, wide-spread implications for global health. Previous work has established common phenotypic comorbidity among these disorders, as well as shared genetic variation underlying them both. We used genomic structural equation modeling to investigate the shared genetics of internalizing, externalizing, and alcohol use traits, as well as to explore whether...

Topics

Humans
Alcohol Drinking
Female
Male
Adult
Mental Disorders
Comorbidity
Genetic Predisposition to Disease
Phenotype
Alcoholism
Middle Aged

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Finland

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Identifiers

PMID: 38375614
DOI: 10.1002/ajmg.b.32975
PMCID: PMC11147714

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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