Article

IFIT3 Knockdown Attenuates Pressure-Overload-Induced Cardiac Inflammation and Remodeling Through a JNK/H3K9 Lactylation-Associated Mechanism

2026-04-11

Abstract excerpt

<title>Abstract</title> <p> <bold>Aims:</bold> Heart failure (HF) is characterized by sustained inflammation and adverse cardiac remodeling, yet the mechanisms underlying macrophage-associated inflammatory activation remain incompletely understood. This study investigated whether the interferon-induced protein <italic>IFIT3</italic> contributes to pressure-overload-induced HF and explored the potential involv...

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Literature Corpus work: bc9dc489-a5b5-5b95-a44d-310fc81ff19e
DOI: 10.21203/rs.3.rs-9292460/v1

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