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Article

ATF3 expression in cardiomyocytes preserves homeostasis in the heart and controls peripheral glucose tolerance.

Cardiovascular research - 1 Feb 2017

Kalfon Roy, Koren Lilach, Aviram Sharon, Schwartz Ortal, Hai Tsonwin, Aronheim Ami

Abstract excerpt

AIMS: Obesity and type 2 diabetes (T2D) trigger a harmful stress-induced cardiac remodeling process known as cardiomyopathy. These diseases represent a serious and widespread health problem in the Western world; however the underlying molecular basis is not clear. ATF3 is an 'immediate early' gene whose expression is highly and transiently induced in response to multiple stressors such as metabolic, oxidative,...

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Source

Identifiers

PMID: 28082453
DOI: 10.1093/cvr/cvw228

Genes

ATF3

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