Article

PP2A-B55α controls keratinocyte adhesion through dephosphorylation of the Desmoplakin C-terminus

2022-10-20

Abstract excerpt

<h4>ABSTRACT</h4> Critical for the maintenance of epidermal integrity and function are attachments between intermediate filaments (IF) and intercellular junctions called desmosomes. The desmosomal cytoplasmic plaque protein desmoplakin (DP) is essential for anchoring IF to the junction. DP-IF interactions are regulated by a phospho-regulatory motif within the DP C-terminus controlling keratinocyte intercellular a...

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Literature Corpus work: ace71623-6e67-5db6-a7ab-48856ec0cbe8
DOI: 10.1101/2022.10.19.512916

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