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Article

The Desmosomal Plaque Proteins of the Plakophilin Family

1 Jan 2010

Abstract excerpt

Three related proteins of the plakophilin family (PKP1_3) have been identified as junctional proteins that are essential for the formation and stabilization of desmosomal cell contacts. Failure of PKP expression can have fatal effects on desmosomal adhesion, leading to abnormal tissue and organ development. Thus, loss of functional PKP 1 in humans leads to ectodermal dysplasia/skin fragility (EDSF) syndrome, a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 20585595
DOI: 10.1155/2010/101452

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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