Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular abnormalities of the desmosomal protein desmoplakin in human disease.

Clinical and experimental dermatology - 1 May 2005

Lai Cheong J E, Wessagowit V, McGrath J A

Abstract excerpt

Desmoplakin is the principal plaque protein of desmosomes, specialized adhesion junctions found in various tissues including skin, heart and meninges. It is an entirely intracellular protein and in keratinocytes desmoplakin binds to other structural components of desmosomes such as cadherins and armadillo proteins, as well as to keratin filaments. Clues to the biological significance of desmoplakin have recently...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autoimmune Diseases
Share to Cytoskeletal Proteins
Share to Desmoplakins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Skin Diseases, Genetic

Share to Skin Neoplasms

Source

Identifiers

PMID: 15807686
DOI: 10.1111/j.1365-2230.2005.01736.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular abnormalities of the desmosomal protein desmoplakin in human disease.PMID 15807686Read ↗

Inherited disorders of desmosomes.Semantic proximity Read ↗

Inherited desmosomal disorders.Semantic proximity Read ↗

Desmosomal genodermatoses.Semantic proximity Read ↗

Human hair abnormalities resulting from inherited desmosome gene mutations.Semantic proximity Read ↗

Mutations in genes encoding desmosomal proteins: spectrum of cutaneous and extracutaneous abnormalities.Semantic proximity Read ↗

The desmosome: cell science lessons from human diseasesSemantic proximity Read ↗

Recessive mutation in desmoplakin disrupts desmoplakin-intermediate filament interactions and causes dilated cardiomyopathy, woolly hair and keratoderma.Semantic proximity Read ↗

Hereditary diseases of desmosomes.Semantic proximity Read ↗

Haploinsufficiency of desmoplakin causes a striate subtype of palmoplantar keratoderma.Semantic proximity Read ↗

Targetting of desmoglein 1 in inherited and acquired skin diseases.Semantic proximity Read ↗

Novel homozygous mutation in DSP causing skin fragility-woolly hair syndrome: report of a large family and review of the desmoplakin-related phenotypes.Semantic proximity Read ↗

Insights from a Desmoplakin Mutation Identified in Lethal Acantholytic Epidermolysis BullosaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.