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Disease stage-specific pathogenicity of CD138 (syndecan 1)-expressing T cells in systemic lupus erythematosus

2020-03-27

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objective</h4> To identify and characterize CD138 (syndecan 1)-expressing T cells in SLE-prone mice. <h4>Methods</h4> We characterized CD138-expressing T cells in MRL/Lpr mice by flow cytometry assay and by gene analysis. Functional properties of TCRβ+CD138+ cells were assessed either by activating through TCR or by co-incubating with purified B cells in the presence of auto-antigens. Puri...

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Literature Corpus work
ac9c3cd0-8666-52b5-9dbb-56287cd7ff83
DOI
10.1101/2020.03.25.008995
Open publication

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Disease stage-specific pathogenicity of CD138 (syndecan 1)-expressing T cells in systemic lupus erythematosusDOI 10.1101/2020.03.25.008995
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