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Article

Clonal relationships between Tph and Tfh cells in patients with SLE and in murine lupus

2025-09-12

Abstract excerpt

<title>Abstract</title> <p>Pathologic T cell-B cell interactions drive disease in systemic lupus erythematosus (SLE). The T cells that activate B cell responses include T peripheral helper (Tph) and T follicular helper (Tfh) cells, yet the developmental and clonal relationships between these B cell-helper T cell populations are unclear. Here we use T cell receptor (TCR) profiling to demonstrate substantial clonal...

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Literature Corpus work
b4010d49-e001-5305-8025-bcbfa46fef1f
DOI
10.21203/rs.3.rs-7472890/v1
Open publication

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Clonal relationships between Tph and Tfh cells in patients with SLE and in murine lupusDOI 10.21203/rs.3.rs-7472890/v1
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