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Article

Dysregulated Ribosome Biogenesis Reveals Therapeutic Liabilities in Cancer.

Trends in cancer - 1 Jan 2021

Bursać Slađana, Prodan Ylenia, Pullen Nick, Bartek Jiri, Volarević Siniša

Abstract excerpt

Ribosome biogenesis (RiBi) is one of the most complex and energy demanding processes in human cells, critical for cell growth and proliferation. Strong causal links between inherited and acquired impairment in RiBi with cancer pathogenesis are emerging, pointing to RiBi as an attractive therapeutic target for cancer. Here, we will highlight new knowledge about causes of excessive or impaired RiBi and the impact...

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Identifiers

PMID: 32948502
DOI: 10.1016/j.trecan.2020.08.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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