Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

Decoding the ribosome's hidden language: rRNA modifications as key players in cancer dynamics and targeted therapies

1 May 2024

Abstract excerpt

Ribosomal RNA (rRNA) modifications, essential components of ribosome structure and function, significantly impact cellular proteomics and cancer biology. These chemical modifications transcend structural roles, critically shaping ribosome functionality and influencing cellular protein profiles. In this review, the mechanisms by which rRNA modifications regulate both rRNA functions and broader cellular...

Source

Identifiers

PMID: 38797935
DOI: 10.1002/ctm2.1705

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Decoding the ribosome's hidden language: rRNA modifications as key players in cancer dynamics and targeted therapiesPMID 38797935Read ↗

Decoding ribosome complexity: role of ribosomal proteins in cancer and diseaseSemantic proximity Read ↗

Tuning the ribosome: The influence of rRNA modification on eukaryotic ribosome biogenesis and functionSemantic proximity Read ↗

Ribosome Biogenesis and Function in Cancer: From Mechanisms to TherapySemantic proximity Read ↗

Charging the code — tRNA modification complexesSemantic proximity Read ↗

Landscape of the complete RNA chemical modifications in the human 80S ribosome.Semantic proximity Read ↗

tRNA modifications: greasing the wheels of translation and beyondSemantic proximity Read ↗

How Ribosomes Translate Cancer.Semantic proximity Read ↗

tRNA modifications and tRNA-derived small RNAs: new insights of tRNA in human diseaseSemantic proximity Read ↗

Dysregulation of tRNA methylation in cancer: Mechanisms and targeting therapeutic strategiesSemantic proximity Read ↗

Ribosomal proteins and human diseases: molecular mechanisms and targeted therapy.Semantic proximity Read ↗

Mitochondrial ribosomal proteins: potential targets for cancer prognosis and therapySemantic proximity Read ↗

Loss of m <sup>1</sup> acp <sup>3</sup> Ψ ribosomal RNA modification is a major feature of cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.