Article

Compound-specific DNA adduct profiling with nanopore sequencing and IonStats

2025-11-01

Abstract excerpt

<h4> A bstract </h4> Covalently bound DNA adducts are mutation precursors that contribute to aging and diseases such as cancer. Accurate detection of adducts in the genome will shed light on tumorigenesis. Commonly used detection methods are unable to pinpoint the exact genomic locations of adducts. Long-read nanopore sequencing has the potential to accurately detect multiple types of DNA adducts at single-nucl...

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Literature Corpus work: ac7b391f-2a69-505f-b41f-547e0d6c3f3f
DOI: 10.1101/2025.10.31.685820

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