Article
New horizons of DNA adductome for exploring environmental causes of cancer.
Cancer science - 1 Jan 2021
Totsuka Yukari, Watanabe Masatoshi, Lin Yingsong
Abstract excerpt
Chemical carcinogenesis is focused on the formation of DNA adducts, a form of DNA damage caused by covalent binding of a chemical moiety to DNA. The detection of carcinogen-DNA adducts in human tissues, along with demonstration of mutagenicity/carcinogenicity in experimental systems, and validation of adducts as biomarkers of environmental exposure and indicators of cancer risk in molecular epidemiological...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
