Article

Direct Maxillary Sinus Tissue Analysis for T2R38 Polymorphisms: Establishing a Translational Framework in Odontogenic Rhinosinusitis

2026-05-09

Abstract excerpt

Bitter taste receptors (T2Rs), specifically T2R38, are present in the respiratory epithelium and react with bacterial quorum-sensing molecules to induce an innate immunity response. Although T2R38 polymorphisms have been correlated with susceptibility to chronic rhinosinusitis (CRS), they have not yet been explored in odontogenic rhinosinusitis (ORS), a distinct form of CRS with particular microbial and inflammato...

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Literature Corpus work: ac71ce6c-1720-5fcb-a91d-3d84473ba25e
DOI: 10.20944/preprints202605.0589.v1

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