Article
Role of the bitter taste receptor T2R38 in upper respiratory infection and chronic rhinosinusitis.
Current opinion in allergy and clinical immunology - 1 Feb 2015
Lee Robert J, Cohen Noam A
Abstract excerpt
PURPOSE OF REVIEW: Taste receptor family 2 (T2R) bitter taste receptors were originally identified and named on the basis of their role in type 2 taste cells of the tongue, in which they serve to detect the presence of potentially harmful ingested chemicals. In 2009, researchers demonstrated that airway epithelial cells also express T2R receptors, but their role in airway physiology and human disease has only...
Topics
- Animals
- Chronic Disease
- Cilia
- Genetic Predisposition to Disease
- Genotype
- Gram-Negative Bacterial Infections
- Humans
- Nasal Mucosa
- Nitric Oxide
- Polymorphism, Genetic
- Receptors, G-Protein-Coupled