Article
The impact of bitter taste receptor genetics on culturable bacteria in chronic rhinosinusitis.
Rhinology - 1 Mar 2017
Rom D I, Christensen J M, Alvarado R, Sacks R, Harvey R J
Abstract excerpt
BACKGROUND: Extra-oral bitter taste receptors have been associated with innate bacterial defence mechanisms. Genetic variation in T2R38 functionality has been shown to be associated with susceptibility to upper respiratory tract infections and chronic rhinosinusitis (CRS). We sought to independently assess the influence of bitter taste receptor genotype on the presence of culturable bacteria in the sinuses....
Topics
- Adult
- Chronic Disease
- Cross-Sectional Studies
- Eosinophilia
- Female
- Genotype
- Humans
- Male
- Middle Aged
- Paranasal Sinuses
- Rhinitis
- Sinusitis