Article
The correlation of TAS2R38 gene variants with higher risk for chronic rhinosinusitis in Polish patients.
Otolaryngologia polska = The Polish otolaryngology - 31 Oct 2016
Dżaman Karolina, Zagor Mariola, Stachowiak Małgorzata, Bielińska Beata, Sarnowska Elżbieta, Krzeski Antoni, Kantor Ireneusz
Abstract excerpt
BACKGROUND: Bitter taste receptors (T2Rs), especially T2R38s appear as innovative regulators of innate immunity in the respiratory system. The single nucleotide polymorphisms (SNPs) in TAS2R38 gene may contribute to individual differences in susceptibility to respiratory infections especially chronic rhinosinusitis (CRS). TAS2R38 genotypes distribution varies by geographic region, race and ethnicity. The aim of...
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