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Article

Genetic variations in taste receptors are associated with chronic rhinosinusitis: a replication study.

International forum of allergy & rhinology - 1 Mar 2014

Mfuna Endam Leandra, Filali-Mouhim Abdelali, Boisvert Pierre, Boulet Louis-Philippe, Bossé Yohan, Desrosiers Martin

Abstract excerpt

BACKGROUND: Recent evidence implicates polymorphisms of the bitter taste receptor TAS2R38 as defining characteristics in respiratory innate defense that may contribute to the complex genetic and environmental interactions predisposing to chronic rhinosinusitis (CRS). The purpose of this study was to (1) verify whether identified polymorphisms associated with respiratory infection in taste receptors replicate...

Topics

Adult
Canada
Chronic Disease
DNA Mutational Analysis
Disease Progression
Female
Gene Frequency
Genetic Predisposition to Disease
Genome-Wide Association Study
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Middle Aged

Mutation, Missense

Nasal Polyps

Polymorphism, Single Nucleotide

Prospective Studies

Receptors, G-Protein-Coupled

Recurrence

Source

Identifiers

PMID: 24415641
DOI: 10.1002/alr.21275

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-24415641-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Genetic variations in taste receptors are associated with chronic rhinosinusitis: a replication study.PMID 24415641Read ↗

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