Article

Nodal-Induced L1CAM/CXCR4 Subpopulation Sustains Tumor Growth and Metastasis in Colorectal Cancer Derived Organoids.

2020-08-01

Abstract excerpt

<h4>Background: </h4> Colorectal cancer (CRC) is currently the third leading cause for cancer-related mortality. Cancer stem cells have been implicated in colorectal tumor growth, but their specific role in tumor biology, including metastasis, is still uncertain. <h4>Methods: </h4> Increased expression of L1CAM, CXCR4 and NODAL was identified in tumor section of patients with CRC and in Patients-derived-organoids...

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Literature Corpus work: ac59e9eb-c869-5f8a-8dea-9248a7d616c7
DOI: 10.21203/rs.3.rs-48786/v1

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