Article

FUBP1 Promotes Colorectal Cancer Stemness and Metastasis via DVL1-Mediated Activation of Wnt/β-Catenin Signaling

2021-01-25

Abstract excerpt

<h4>Background: </h4> Most colorectal cancer (CRC) patients die from distant metastasis. Approximately 50% of CRC patients develop liver metastases, while 10% to 30% of patients appear pulmonary metastases. The occurrence of metastasis is considered to be almost exclusively driven by cancer stem cells (CSCs) formation. However, the key molecules that confer the stem-transformation of CRC and subsequent metastasis...

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Literature Corpus work: b75a359d-867c-5b8c-add6-14e05a853bfc
DOI: 10.21203/rs.3.rs-152458/v1

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