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Oct4 Gene Expression in Primary Colorectal Cancer Promotes Liver Metastasis

2 May 2019

Abstract excerpt

Purpose. The Oct4 gene plays an important role in undifferentiated embryonic stem cells and regulates stem cell pluripotency. The aim of this study was to examine the relationship between Oct4 expression and liver metastasis of colorectal cancer (CRC) in clinical samples and investigate the role and abilities of Oct4-positive CRC cells. Methods. The study included 158 patients who underwent surgery for CRC...

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PMID: 31191684
DOI: 10.1155/2019/7896524

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