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Colorectal cancer stem cells properties and features: evidence of interleukin-8 involvement

1 Jan 2019

Abstract excerpt

Colorectal cancer (CRC) still remains a disease with high percentage of death, principally due to therapy resistance and metastasis. During the time the hypothesis has been reinforced that CRC stem cells (CRCSC) are involved in allowing intratumoral heterogeneity, drug escape mechanisms and secondary tumors. CRCSC are characterized by specific surface markers (i.e., CD44 and CD133), signaling pathways activation...

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PMID: 35582268
DOI: 10.20517/cdr.2019.56

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