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The regulatory role of cancer stem cell marker gene CXCR4 in the growth and metastasis of gastric cancer

7 Sept 2023

Abstract excerpt

Single-cell RNA sequencing (scRNA-seq) and bulk RNA sequencing (bulk RNA-seq) are increasingly used for screening genes involved in carcinogenesis due to their capacity for dissecting cellular heterogeneity. This study aims to reveal the molecular mechanism of the cancer stem cells (CSCs) marker gene CXCR4 in gastric cancer (GC) growth and metastasis through scRNA-seq combined with bulk RNA-seq. GC-related...

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PMID: 37679408
DOI: 10.1038/s41698-023-00436-2

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