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Article

CD133(+)CXCR4(+) colon cancer cells exhibit metastatic potential and predict poor prognosis of patients.

BMC medicine - 7 Aug 2012

Zhang Shan-shan, Han Zhi-peng, Jing Ying-ying, Tao Shuang-fen, Li Tie-jun, Wang Hao, Wang Yang, Li Rong, Yang Yang, Zhao Xue, Xu Xiao-dong, Yu En-da, Rui Yao-cheng, Liu Hou-jia, Zhang Li, Wei Li-xin

Abstract excerpt

BACKGROUND: Colorectal cancer (CRC), which frequently metastasizes to the liver, is one of the three leading causes of cancer-related deaths worldwide. Growing evidence suggests that a subset of cells exists among cancer stem cells. This distinct subpopulation is thought to contribute to liver metastasis; however, it has not been fully explored in CRC yet. METHODS: Flow cytometry analysis was performed to detect...

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Share to AC133 Antigen
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Epithelial-Mesenchymal Transition

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Source

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Identifiers

PMID: 22871210
DOI: 10.1186/1741-7015-10-85
PMCID: PMC3424958

Genes

CXCR4
CXCL12

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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