Article

A systematic analysis of rodent models implicates adipogenesis and innate immunity in pathogenesis of fatty liver disease

2020-12-15

Abstract excerpt

<h4>Summary</h4> Animal models of human disease are a key component of translational research and yet there is often no consensus on which model is optimal for a particular disease. Here, we generated a database of 3,920 rodent models of non-alcoholic fatty liver disease (NAFLD). Study designs were highly heterogeneous therefore few models had been cited more than once. Analysis of genetic models provided evidenc...

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Literature Corpus work: ac50b014-f46d-5d90-8ff5-696dc31c8c62
DOI: 10.1101/2020.12.15.422799

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