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Article

Utilization of animal models to investigate nonalcoholic steatohepatitis-associated hepatocellular carcinoma.

Oncotarget - 5 Jul 2016

Wu Jian

Abstract excerpt

Nonalcoholic fatty liver disease (NAFLD) comprises a spectrum of liver disorders with fat accumulation from simple fatty liver, nonalcoholic steatohepatitis (NASH), fibrosis/cirrhosis and NAFLD/NASH-associated hepatocellular carcinoma (HCC). NASH is a progressive form of NAFLD and requires medical attention. One of 5-10 NASH patients may progress to end-state liver disease (ESLD or cirrhosis) in 5-10 years;...

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Identifiers

PMID: 27072576
DOI: 10.18632/oncotarget.8641
PMCID: PMC5173170

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