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Fat and Sugar-A Dangerous Duet. A Comparative Review on Metabolic Remodeling in Rodent Models of Nonalcoholic Fatty Liver Disease.

Nutrients - 24 Nov 2019

Simoes Ines C M, Janikiewicz Justyna, Bauer Judith, Karkucinska-Wieckowska Agnieszka, Kalinowski Piotr, Dobrzyń Agnieszka, Wolski Andrzej, Pronicki Maciej, Zieniewicz Krzysztof, Dobrzyń Paweł, Krawczyk Marcin, Zischka Hans, Wieckowski Mariusz R, Potes Yaiza

Abstract excerpt

Nonalcoholic fatty liver disease (NAFLD) is a common disease in Western society and ranges from steatosis to steatohepatitis to end-stage liver disease such as cirrhosis and hepatocellular carcinoma. The molecular mechanisms that are involved in the progression of steatosis to more severe liver damage in patients are not fully understood. A deeper investigation of NAFLD pathogenesis is possible due to the many...

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Identifiers

PMID: 31771244
DOI: 10.3390/nu11122871
PMCID: PMC6950566

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Source receipt: pubmed, retrieved 7 Sept 2026.

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