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Article

Non-alcoholic steatohepatitis: what can we learn from animal models?

Current medicinal chemistry - 1 Jan 2012

Almonacid-Urrego C C, Sánchez-Campos S, Tuñón M J, González-Gallego J

Abstract excerpt

Non-alcoholic fatty liver disease (NAFLD) is one of the most frequent causes of abnormal liver function and correlates with central adiposity, obesity, insulin resistance, the metabolic syndrome and type 2 diabetes mellitus. The pathological spectrum of NAFLD ranges from fatty liver to non-alcoholic steatohepatitis (NASH), advanced fibrosis, cirrhosis, and even hepatocellular carcinoma. Though NAFLD and NASH are...

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PMID: 22360487
DOI: 10.2174/092986712799462586

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