Article
Animal models of non-alcoholic fatty liver disease: current perspectives and recent advances.
The Journal of pathology - 1 Jan 2017
Lau Jennie Ka Ching, Zhang Xiang, Yu Jun
Abstract excerpt
Non-alcoholic fatty liver disease (NAFLD) is a continuous spectrum of diseases characterized by excessive lipid accumulation in hepatocytes. NAFLD progresses from simple liver steatosis to non-alcoholic steatohepatitis and, in more severe cases, to liver fibrosis, cirrhosis, and hepatocellular carcinoma (HCC). Because of its growing worldwide prevalence, various animal models that mirror both the histopathology...
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