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A new dietary rat model fully recapitulates metabolic dysfunction-associated steatotic liver disease pathophysiology and mimics human disease with advanced liver fibrosis and portal hypertension

2025-06-25

Abstract excerpt

<title>Abstract</title> <p> <bold>Background and Aims:</bold> For decades, investigators have pursued the development of a comprehensive rodent model that fully recapitulates the pathophysiology of metabolic dysfunction-associated steatotic liver disease (MASLD) pathophysiology and mimics human disease. Dietary models are considered the most reliable in terms of reproducing human disease; however, no dietary ro...

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Literature Corpus work
872c6915-f3b7-5355-814d-39d25b06300e
DOI
10.21203/rs.3.rs-6376882/v1
Open publication

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