Article

Graves' Disease: In Silico Design of Hybrid Molecule Targeting the Thyroid-stimulating Hormone Receptor

2024-04-08

Abstract excerpt

<title>Abstract</title><p><bold>Introduction</bold>Graves' disease (GD), an autoimmune disorder characterized by hyperthyroidism and the production of autoantibodies targeting the thyroid-stimulating hormone receptor (TSHR), poses a considerable challenge in clinical management. Antithyroid medications block thyroid hormone synthesis and are usually the first-line treatment. In recent years, the advent of computat...

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Literature Corpus work: ac4b7750-eaeb-56c0-8829-57f8ca6b40ac
DOI: 10.21203/rs.3.rs-4220125/v1

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