Article

Metformin-Mediated Modulation of the AMPK/mTOR Axis in Hashimoto’s Thyroiditis: A Network Pharmacology and Molecular Docking Investigation

2026-06-05

Abstract excerpt

<title>Abstract</title> <p> <bold>Introduction:</bold> Hashimoto’s thyroiditis (HT) is the most prevalent organ-specific autoimmune disorder worldwide, characterized by lymphocytic thyroid infiltration and the presence of circulating anti-thyroid autoantibodies. Conventional levothyroxine replacement normalizes circulating thyroid hormone levels but is fundamentally incapable of interrupting the underlying auto...

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Literature Corpus work: ded45603-2c56-5a01-a0a2-879c7f2e3d8d
DOI: 10.21203/rs.3.rs-9904807/v1

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