Article

Origin of diverse phosphorylation patterns in the ERBB system

2020-09-25

Abstract excerpt

Intercellular signals induce various cellular responses, including growth, proliferation, and differentiation, via the dynamic processes of signal transduction pathways. For cell-fate decisions, ligand-binding induces the phosphorylation of ERBB receptors, which in turn activate downstream molecules. The ERBB family includes four subtypes, which diverged through two gene duplications from a common ancestor, of dif...

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Literature Corpus work: ac0c9f0c-b0d6-591e-981d-5169010cca10
DOI: 10.1101/2020.09.25.313965

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