Article
Analysis of regulatory mechanism after ErbB4 gene mutation based on local modeling methodology.
Genetics and molecular research : GMR - 13 May 2016
Chen C L, Zhao J W
Abstract excerpt
ErbB4 is an oncogene belonging to the epidermal growth factor receptor family and contributes to the occurrence and development of multiple cancers, such as gastric, breast, and colorectal cancers. Therefore, studies of the regulation of ErbB4 in cancerigenic pathway will advance molecular targeted therapy. Advanced bioinformatic analysis softwares, such as ExPASy, Predictprotei, QUARK, and I-TASSER, were used to...
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