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Article

ErbB Receptors and Cancer.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2017

Wang Zhixiang

Abstract excerpt

The ErbB receptor family, also known as the EGF receptor family or type I receptor family, includes the epidermal growth factor (EGF) receptor (EGFR) or ErbB1/Her1, ErbB2/Her2, ErbB3/Her3, and ErbB4/Her4. Among all RTKs, EGFR was the first RTK identified and the first one linked to cancer. Thus, EGFR has also been the most intensively studied among all RTKs. ErbB receptors are activated after homodimerization or...

Topics

Active Transport, Cell Nucleus
Animals
ErbB Receptors
Gene Expression Regulation, Neoplastic
Humans
Ligands
Multigene Family
Mutation
Neoplasms
Phosphorylation
Prognosis
Protein Binding

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Protein Interaction Domains and Motifs

Protein Multimerization

Signal Transduction

Source

Identifiers

PMID: 28791631
DOI: 10.1007/978-1-4939-7219-7_1

Genes

EGFR
EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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