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Article

Phosphoproteomics-based modeling defines the regulatory mechanism underlying aberrant EGFR signaling.

PloS one - 10 Nov 2010

Tasaki Shinya, Nagasaki Masao, Kozuka-Hata Hiroko, Semba Kentaro, Gotoh Noriko, Hattori Seisuke, Inoue Jun-ichiro, Yamamoto Tadashi, Miyano Satoru, Sugano Sumio, Oyama Masaaki

Abstract excerpt

BACKGROUND: Mutation of the epidermal growth factor receptor (EGFR) results in a discordant cell signaling, leading to the development of various diseases. However, the mechanism underlying the alteration of downstream signaling due to such mutation has not yet been completely understood at the s...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21085658
DOI: 10.1371/journal.pone.0013926
PMCID: PMC2978091

Genes

EGFR
EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21085658-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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