Article

Single-cell Atlas Unveils Cellular Heterogeneity and Novel Markers in Human Neonatal and Adult Intervertebral Discs

2021-10-21

Abstract excerpt

<h4>SUMMARY</h4> The origin, composition, distribution, and function of cells in the human intervertebral disc (IVD) has not been fully understood. Here, cell atlases of both human neonatal and adult IVDs have been generated and further assessed by gene ontology pathway enrichment, pseudo-time trajectory, histology, and immunofluorescence. Comparison of cell atlases revealed the presence of two sub-populations of...

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Literature Corpus work: abe44721-d54d-51c6-9e5e-a83284fbbc26
DOI: 10.1101/2021.10.20.465219

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