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A single-cell transcriptional atlas reveals resident progenitor cell niche functions in TMJ disc development and injury

14 Feb 2023

Abstract excerpt

Abstract The biological characteristics of the temporomandibular joint disc involve complex cellular network in cell identity and extracellular matrix composition to modulate jaw function. The lack of a detailed characterization of the network severely limits the development of targeted therapies for temporomandibular joint-related diseases. Here we profiled single-cell transcriptomes of disc cells from mice at...

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PMID: 36788226
DOI: 10.1038/s41467-023-36406-2

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