Article

Generalized peakgroup scoring boosts identification rates and accuracy in mass spectrometry based discovery proteomics

2022-11-04

Abstract excerpt

The statistical validation of peptide and protein identifications in mass spectrometry proteomics is a critical step in the analytical workflow. This is particularly important in discovery experiments to ensure only confident identifications are accumulated for downstream analysis and biomarker consideration. However, the inherent nature of discovery proteomics experiments leads to scenarios where the search space...

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Literature Corpus work: abc1d2d1-12a6-5c8a-b20f-c05f0d4ec4ea
DOI: 10.1101/2022.11.03.515031

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