Article
Statistical Evaluation of Labeled Comparative Profiling Proteomics Experiments Using Permutation Test.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2017
Nguyen Hien D, McLachlan Geoffrey J, Hill Michelle M
Abstract excerpt
Comparative profiling proteomics experiments are important tools in biological research. In such experiments, tens to hundreds of thousands of peptides are measured simultaneously, with the goal of inferring protein abundance levels. Statistical evaluation of these datasets are required to determine proteins that are differentially abundant between the test samples. Previously we have reported the non-normal...
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