Article

Paradigm shift in biomarker translation: a pipeline to generate clinical grade biomarker candidates from DIA-MS discovery

2024-03-22

Abstract excerpt

Clinical biomarker development has been stymied by inaccurate protein quantification from mass spectrometry (MS) discovery data and a prolonged validation process. To mitigate these issues, we created the Targeted Extraction Assessment of Quantification (TEAQ) software package. This innovative tool uses the discovery cohort analysis to select precursors, peptides, and proteins that adhere to established targeted a...

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Literature Corpus work: 13539d8f-2923-51e8-914e-e1d189532c30
DOI: 10.1101/2024.03.20.586018

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