Article

APIR: Aggregating Universal Proteomics Database Search Algorithms for Peptide Identification with FDR Control

2021-09-10

Abstract excerpt

Advances in mass spectrometry (MS) have enabled high-throughput analysis of proteomes in biological systems. The state-of-the-art MS data analysis relies on database search algorithms to quantify proteins by identifying peptide-spectrum matches (PSMs), which convert mass spectra to peptide sequences. Different database search algorithms use distinct search strategies and thus may identify unique PSMs. However, no...

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Literature Corpus work: f98917c9-7127-554a-9498-10a1f22e73e2
DOI: 10.1101/2021.09.08.459494

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