Article

From variability to consensus: rescoring harmonizes peptide identification across diverse search engines and datasets

2026-03-06

Abstract excerpt

Peptide-spectrum match (PSM) rescoring has become standard in proteomics workflows, improving peptide identification accuracy across diverse search engines. Despite the availability of multiple rescoring strategies, systematic comparisons spanning several search engines, datasets, and database configurations remain limited. Here, we benchmarked seven publicly available search engines, evaluating standard target-de...

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Literature Corpus work: eff5cda1-0646-5d59-8355-6e8c0d5df0c7
DOI: 10.64898/2026.03.04.709532

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