Article
PSEA-Quant: a protein set enrichment analysis on label-free and label-based protein quantification data.
Journal of proteome research - 5 Dec 2014
Lavallée-Adam Mathieu, Rauniyar Navin, McClatchy Daniel B, Yates John R
Abstract excerpt
The majority of large-scale proteomics quantification methods yield long lists of quantified proteins that are often difficult to interpret and poorly reproduced. Computational approaches are required to analyze such intricate quantitative proteomics data sets. We propose a statistical approach to computationally identify protein sets (e.g., Gene Ontology (GO) terms) that are significantly enriched with abundant...
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