Article

A Pre-computed Probabilistic Molecular Search Engine for Tandem Mass Spectrometry Proteomics

2020-02-07

Abstract excerpt

Mass spectrometry methods of peptide identification involve comparing observed tandem spectra with in-silico derived spectrum models. Presented here is a proteomics search engine that offers a new variation of the standard approach, with improved results. The proposed method employs information theory and probabilistic information retrieval on a pre-computed and indexed fragmentation database generating a peptide...

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Literature Corpus work: c21ec176-fc2c-5a41-b493-997c7af9aba7
DOI: 10.1101/2020.02.06.937870

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