Article

ABERRANT IMMUNE PROGRAMMING IN NEUTROPHILS IN CYSTIC FIBROSIS

2023-01-25

Abstract excerpt

<h4>ABSTRACT</h4> Cystic fibrosis (CF) is a life-shortening genetic disorder, caused by mutations in the gene that encodes Cystic Fibrosis Transmembrane-conductance Regulator (CFTR), a cAMP-activated chloride and bicarbonate channel. Although multiple organ systems can be affected, CF lung disease claims the most morbidity and mortality due to chronic bacterial infection, persistent neutrophilic inflammation, and...

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Literature Corpus work: abb0b9b5-9c1a-5173-8a11-34519d595fa1
DOI: 10.1101/2023.01.22.23284619

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